Anthrax: (N) Bacillus anthracis, Splenic Fever, Charbon, Milzbrand. Quarantine, proper disposal, clean and disinfect premises, isolate animals, recommend vaccination program, control scavengers. Diagnosis may be made by clinical signs and demonstrations of bacillus organism on direct microscopic examination of blood smears. (B051)

Bluetongue: (N) Orbivirus. Presumptive diagnosis based upon clinical signs and positive serology (cELISA, SN). Definitive diagnosis requires virus isolation. (A090)

Brucellosis: (N) Brucella spp., Contagious abortion, Bang's Disease. Cooperative USDA, APHIS, VS/State eradication program. Canines: discuss public health significance and neutering with owner (see individual species). (B103)

Contagious Bovine Pleuropneumonia: (N) Mycoplasma mycoides mycoides. FOREIGN ANIMAL DISEASE. (A060)

Echinococcosis / Hydatidosis: (N) Diagnose by finding proglottids or eggs in feces. (B053)

Exotic Myiasis: Fly larvae.

Foot and Mouth Disease: (N) Enterovirus, family Picornaviridae. FOREIGN ANIMAL DISEASE. (A010)

Heartwater: (N) Cowdria rumanantium. FOREIGN ANIMAL DISEASE. (B055)

Leptospirosis: (N) Leptospira spp. Presumptive diagnosis based on fourfold or greater increase of titer in paired serum samples using the MAT in non-vaccinated animals. Definitive diagnosis requires demonstration and identification of the organism in culture or via PCR, IHC, FA, or silver stain. (B056)

Lumpy Skin Disease: (N) Poxvirus. FOREIGN ANIMAL DISEASE. (A070)

Malignant Catarrhal Fever: (N) Alcelaphine herpesvirus 1, sheep associated agent of MCF, Snotsiekte, Gangrenous Coryza. Presumptive diagnosis can be made based on serology(cELISA, SN, IFA) and/or characteristic histological lesions. Definitive diagnosis requires demonstration of the agent via virus isolation or PCR. (B114)

Paratuberculosis: (N) Mycobacterium paratuberculosis, Johne's Disease. Presumptive diagnosis is based on compatible clinical signs and histopathology and/or serology (AGID, ELISA) or demonstration of acid-fast organisms in lesions. Definitive diagnosis requires demonstration of M. paratuberculosis by culture or PCR/DNA probe. Work cooperatively with private practitioners to encourage producers to participate in the National Voluntary Johne's Disease Control Program. (B059)

Peste des Petits Ruminants: Morbillivirus. FOREIGN ANIMAL DISEASE. (A050)

Pseudorabies: (N) Herpesvirus, Aujeszky's Disease, Mad Itch. Definitive diagnosis is based on the results of USDA-approved serologic tests or virus isolation and identification and concurrence of the State Chief Animal Health Official and Federal Area Veterinarian-in-Charge. Positive premises quarantined. Cooperative federal-state-industry eradication program. (B052)

Rabies: (N) Lyssavirus. Diagnosis may be based on either a specific FA test (with or without mouse inoculation) or typical histopathologic lesions (Negri bodies). Positive animals are traced to owner and exposed people and animals. Work closely with MDCH and animal control officers. Quarantines are issued if necessary. Guidelines of the current Compendium of Animal Rabies Control prepared by the National Association of State Public Health Veterinarians, Inc. are followed. (B058)

Rift Valley Fever: (N) Bunyavirus. FOREIGN ANIMAL DISEASE. (A080)

Rinderpest: (N) Morbillivirus. (A040)

Screwworm: (N) Cochliomyia (callitroga) hominivorax. FOREIGN ANIMAL DISEASE. Quarantine afflicted animal(s). (B060)

Toxic Substance Contamination: Any substance, including drug residues, in a concentration which alone or in combination meet any of the following criteria are reportable: (1) Any suspected or known toxicities of unknown origin. (2) If the animal(s) affected is/are a potential source of toxicological contamination to humans or other animals. (3) If the source of the toxicological agent or exposure is potentially hazardous to humans or other animals.

Transmissible Spongiform Encephalopathy (TSE): Examples include, but are not limited to, the following diseases: Feline Spongiform Encephalopathy, Bovine Spongiform Encephalopathy, Chronic Wasting Disease, Scrapie. See individual species.

Tuberculosis: (N) Mycobacterium tuberculosis, M. avium, M. bovis, TB. Diagnosis is based upon positive skin tests, gross lesions at necropsy, histopathology, culture, and PCR tests.

Cooperative state-federal eradication program for bovine, bison, and captive cervids. (B105) (B303)

Vesicular Stomatitis: Rhabdovirus. FOREIGN ANIMAL DISEASE. (A020)

West Nile Virus Encephalitis: Arthropod borne flavivirus. Potential zoonosis from mosquitos to humans. Cooperative control program with Michigan Department of Community Health and local authorities.

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