Viral Serology: This unit provides serologic testing for viral diseases. Most IgG assays require paired sera for analysis. IgM testing is done on single sera, some by special request only.

Viral Isolation: This unit assists the medical and public health communities in establishing the cause of viral disease through cell culture and/or detection techniques and immunological assays.

Rabies: This unit provides testing of nonvaccinated suspect animals that have exposed a person.

Viral Molecular:  This unit provides molecular expertise for new assay development as well as a battery of assays for pre-approved testing.

Patty Clark, M.P.H., Unit Manager
517-335-8102
clarkp@michigan.gov

TESTING PERFORMED WITHIN THIS UNIT:

The following is a listing of assays/analytes tested in the Viral Serology / Viral Isolation/Viral Molecular Unit at the Michigan Department of Community Health, Bureau of Laboratories.

Testing denoted by italics require prior approval.

Viral Serology:

• Arbovirus IgM (CGV, SLE, EEE, WNV)
• Arbovirus PRNT (CGV, SLE, EEE, WNV)
• CMV IgG
• HBsAg (Hepatitis B Surface Antigen)
• HBV Antibody (anti-HBs)
• Hepatitis A (IgM)
• Hepatitis C Antibody - NOTE: This is a screening EIA whose test algorithm follows the 2003 CDC guidelines.
• HSV IgG
• Measles IgG
• Mumps IgG
• Rabies Neutralizing Antibody Serology 
• Rubella IgG
• Rubella IgM
• Varicella zoster IgG
  
  NOTE: Health Care Worker and Medical/Nursing Student Immune Status testing is available on a fee-for-service basis. Health care worker immune status testing includes Varicella zoster IgG, Measles IgG and Rubella IgG. Medical/Nursing student antibody testing includes Varicella zoster IgG, Measles IgG, Rubella IgG, Mumps IgG and anti-HBs. See our Test Request Form page for further information.
  

Viral Isolation:

• Adenovirus by culture

• Chlamydia trachomatis  by culture

• Cytomegalovirus by culture

• Enterovirus by culture

• Herpes simplex virus by culture

• Mumps virus by culture

• Rabies virus (animal)

• Respiratory viruses by culture

• Vaccinia/Variola/Pox Virus (by DFA)

• Varicella-zoster virus by culture

• Varicella-zoster virus by DFA

Electron Microscopy:

• Norovirus - Done as a part of Epidemiologic investigations, as needed.
• Poxvirus - Done as a part of bioterrorism investigations, as needed.

Molecular Virology:

Prior approval throught the Virology Section Manager is required before specimen submission.

• Enterovirus
• HIV-1 Genotype Analysis
• Influenza A, H5
• Mumps
• Norovirus
• Pox Virus
• Respiratory Pathogens

REV.  3/28/2008