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Post-Exposure Prophylaxis (PEP)

Post-exposure prophylaxis (PEP) is a preventive treatment that can reduce the chance that a person who is exposed to HIV will get HIV.

PEP treatment involves two to three different antiretroviral medicines that work together to prevent HIV from making copies of itself and spreading through the body. To be effective, the medicines must be started as soon as possible—but not more than 72 hours (3 days) after—possible exposure to the virus. They must be taken on schedule for 28 days.

PEP medicines can reduce the chance of getting HIV, but they are not always effective. Taking PEP does not guarantee that a HIV infection will be prevented.

For more information about PEP, visit PEP (CDC).

HIV Prevention – Let’s Talk About PEP

Find a PEP Provider or Navigator

  • Michigan PEP Provider Directory
    PEP providers are medical professionals that can prescribe post exposure prophylaxis (PEP), order necessary laboratory testing, and conduct medication adherence counseling.
  • Michigan PrEP and PEP Navigator Directory
    PEP navigation is a service that is designed to assist individuals in accessing and adhering to PEP for 28 days. PEP navigators work to tailor education and support to the client to meet their individual needs. Navigation services include identifying and linking people to a PEP provider, assisting the individual to access PEP medications and appropriate laboratory testing, and identifying/reducing barriers to PEP care.

Provider Resources