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Michigan BioTrust for Health- Dried Blood Spot Research
Blood Spot Research
Dried blood spots (DBS) leftover after newborn screening may be used for medical and public health research studies to better understand underlying causes of disease and possible interventions to improve health outcomes. The BioTrust for Health program at MDHHS oversees the research use of these residual specimens. The availability of DBS for research depends on the consent requirements in place at the time of collection. All research must be approved by MDHHS through the BioTrust application process. This process includes review by the MDHHS Institutional Review Board and the BioTrust Scientific Advisory Board.
This table provides a summary and current status of research requesting blood spots from Michigan.
MDHHS, in collaboration with our BioTrust Community Values Advisory Board, has developed policies to outline how DBS can be used in medical and public health research studies:
Guidelines for Research Use of Dried Blood Spots - DHHS Policy 114
Guidelines for Review and Approval of Research Using Dried Blood Spots - DHHS Policy 115
Information for Researchers
Research teams interested in learning more about blood spot research in Michigan can download the BioTrust Research Manual. This manual describes:
- DBS availability for research.
- Policies outlining the appropriate use of DBS in health research.
- How to apply to MDHHS to use DBS for research purposes.
- Storage conditions for DBS and more.
MDHHS Institutional Review Board
- Form: IRB Initial Review Application
- Form: IRB Abbreviated Initial Review Application
- Resource: Selecting an Application and Applying. This webpage provides information on which MDHHS IRB application is appropriate.
Form: BioTrust Request for Samples
Completed applications for research using blood spots can be submitted by email to BioTrust@michigan.gov.