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PrEP for Women

Pre-exposure prophylaxis (PrEP) is safe and effective for cisgender and transgender women. PrEP medications approved for use by
people who have receptive vaginal sex:

  • Truvada (or its generic equivalent), a pill taken every day.
  • Apretude, a shot every two months.

Descovy has not been approved for individuals assigned female at birth.

Can I take PrEP while on birth control?

There are no known interactions between PrEP and hormone-based birth control (e.g., pill, patch, ring, shot, implant, or IUD). It is safe to use both at the same time.

Can I take PrEP during pregnancy or while breast/chest feeding?

PrEP may be a good option to help prevent you and your baby from getting HIV while you are trying to get pregnant, during pregnancy or while breast/chest feeding. Talk to your health care provider about your options to prevent HIV.

Does PrEP impact hormone replacement therapy (HRT)?

There is no evidence that PrEP will interfere with hormone therapy. Discuss your particular concerns with your health care provider.

Does PrEP prevent STIs or pregnancy?

While PrEP protects against HIV, it does not protect against other sexually transmitted infections (STIs) or pregnancy. Condoms are the best option to protect against STIs and offer additional protection against HIV when using PrEP.


For more information on PrEP for women, visit:

For more information on HIV and women, visit: