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PrEP (Pre-Exposure Prophylaxis)

PrEP (pre-exposure prophylaxis) is a medication that can be taken to reduce an individual's chances of getting HIV through sex or injection drug use. PrEP is for people who do not have HIV now, but who are at risk of getting it. When someone who has been taking PrEP is exposed to HIV through sex or injection drug use, the medicines can keep the virus from establishing a permanent infection. Taking PrEP as prescribed by a healthcare provider can reduce your chances of getting HIV by up to 99% for sexual encounters and 74% for injection drug use.

To hear stories from real people who are taking PrEP to prevent HIV, visit: Let's Talk About PrEP - Greater Than AIDS.

PrEP (Pre-Exposure Prophylaxis)

Medication also can be taken following a possible exposure to HIV to help prevent transmission of the virus. In such cases, the medications are referred to as PEP (post-exposure prophylaxis). Both PrEP and PEP can be prescribed by a doctor, physician assistant, or nurse practitioner.>

Find a PrEP Provider or Navigator

PrEP Providers are medical professionals that can prescribe PrEP, order necessary laboratory testing, and conduct medication adherence counseling. 

PrEP Navigation is a service that is designed to assist individuals in starting and staying on PrEP. PrEP Navigators work to tailor education and support to the client in order to meet their individual needs. Navigation services include identifying and linking people to a PrEP Provider for care, assisting with health insurance and financial assistance programs, and identifying/reducing barriers to care.

To locate a PrEP Provider or Navigator close to you, view the interactive map or see the directories for a full list of PrEP Providers and Navigators in Michigan.

If there is no provider in your area, please contact MDHHS Public Health Detailer:
Mark Schaecher, PAC
Public Health Detailer, MDHHS

Learn More About PrEP

  • PrEP might be right for you if you relate to any of the following:

    • Infrequent or inconsistent condom use during sex with partners.PrEP Icons
    • Having condomless sex with someone whose HIV status is unknown.
    • You have had a sexually transmitted infection (STI) in the past six months.
    • Sharing needles or other equipment to inject drugs.
    • Having sex with someone with HIV who is not in care or has not been undetectable for six months.
    • Exchanging sex for money, drugs, housing, or other things.

    For more information on if PrEP is right for you, visit: Deciding to Take PrEP - CDC

  • PrEP works by preventing HIV from replicating itself in the body if an individual is exposed to the virus. PrEP should be taken as prescribed by a healthcare provider. PrEP does not treat or cure HIV and should not be used by people currently with HIV. PrEP does not protect against sexually transmitted infections (STIs). Using condoms while on PrEP is highly recommended.

    Things to Note:

    • PrEP can be taken for any amount of time.PrEP 1
    • It is important that you only start or stop taking PrEP with the help of a healthcare provider.
    • Do not share PrEP with someone who has not been prescribed PrEP.

    For more information on how PrEP works, visit: PrEP - CDC

  • PrEP is safe and effective for cisgender and transgender women. Truvada and its generic have been approved for adults and adolescents weighing at least 77 pounds. Descovy has not been approved for individuals assigned female at birth.

    PrEP can be taken safely with birth control - there are no drug interactions.

    PrEP can also be safely taken during pregnancy.

    PrEP and hormone therapy can be taken at the same time.

    For more information on PrEP and Women, visit:

  • Post-Exposure Prophylaxis (PEP) is a preventive treatment that can reduce the chance that a person who is exposed to HIV will become HIV-positive.

    PEP treatment involves two to three different antiretroviral medicines that work together to prevent HIV from making copies of itself and spreading through the body. To be effective, the medicines must be started as soon as possible - but not more than 72 hours (3 days) after - possible exposure to the virus. They also must be taken on schedule for 28 days.

    PEP medicines can reduce the risk of becoming HIV-positive. But, they are not always effective. Taking PEP does not guarantee that a HIV infection will be prevented.

    For more information about PEP, visit: PEP - CDC

  • Human Immunodeficiency Virus (HIV) damages the body's immune system. If left untreated, HIV reduces the body's ability to fight off illnesses.

    Ways HIV Can be Transmitted:

    • By having vaginal, anal, or oral sex without a condom.
    • By sharing needles or equipment (works) when injecting drugs.
    • From birthing person to child during pregnancy, delivery, and breast feeding.

    You cannot get HIV by donating blood or through casual contact such as hugging or shaking hands.

    For more information about HIV, visit: HIV Basics - CDC


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