MIS-C Reporting


What is MIS-C?

Multisystem Inflammatory Syndrome in Children (MIS-C) is a condition in children and adolescents under 21 years of age where multiple organ systems become inflamed or dysfunctional which occurs in association with illness. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, bloodshot eyes, or feeling extra tired. We do not yet know what causes MIS-C. However, many children with MIS-C were infected with the virus that causes COVID-19, or had been around someone with COVID-19.

Health care providers and local health departments are asked to maintain a high degree of suspicion for MIS-C in pediatric and adolescent patients presenting with symptoms similar to Kawasaki Disease or ill individuals who have been previously exposed to COVID-19 with signs and symptoms. Patients have presented with persistent fever*, hypotension, multiorgan (cardiac, gastrointestinal, renal, hematologic, dermatologic, and neurologic) involvement, and elevated inflammatory markers. Respiratory symptoms have been present in some, but are not a common finding.

*Persistent fever is a measured fever of 100.4°F (38.0°C) or greater for at least 24 hours, or report of subjective fever lasting at least 24 hours.

Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C)
Data will be updated on the first and third Thursdays of the month.


Multisystem Inflammatory Syndrome in Children (MIS-C) Michigan Data Summary 10/07/2021
# Cases Confirmed and Reported to CDC* 169
MIS-C associated Deaths 5 or fewer
Cases admitted to ICU  119 (70.2%)
Onset Date Range 4/14/20 to 9/19/2021
Age Range 0-20 years

*Meets CDC Case definition


Age Group Count % Race Count %
0-4 yrs 44 26.1% Black/African American 72 42.6%
5-10 yrs 69 40.8% Caucasian 70 41.4%
>10 yrs 56 33.1% All Others / Unknown 27 16.0%
Gender Counts % Ethnicity Count %
Male 98 57.7% Not Hispanic or Latino 120 71.0%
Female 71 42.3% Hispanic or Latino 14 8.3%
Unknown 0 0.0% Unknown 35 20.7%


MIS-C Weekly Chart

Red shading indicates the expected reporting lag for new cases. Cases with onset dates in this time period may not have been detected or reported yet.  

Map by region of case counts