MIS-C Reporting

What is MIS-C?

Multisystem Inflammatory Syndrome in Children (MIS-C) is a condition in children and adolescents under 21 years of age where multiple organ systems become inflamed or dysfunctional which occurs in association with illness. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, bloodshot eyes, or feeling extra tired. We do not yet know what causes MIS-C. However, many children with MIS-C were infected with the virus that causes COVID-19, or had been around someone with COVID-19.

Health care providers and local health departments are asked to maintain a high degree of suspicion for MIS-C in pediatric and adolescent patients presenting with symptoms similar to Kawasaki Disease or ill individuals who have been previously exposed to COVID-19 with signs and symptoms. Patients have presented with persistent fever*, hypotension, multiorgan (cardiac, gastrointestinal, renal, hematologic, dermatologic, and neurologic) involvement, and elevated inflammatory markers. Respiratory symptoms have been present in some, but are not a common finding.

*Persistent fever is a measured fever of 100.4°F (38.0°C) or greater for at least 24 hours, or report of subjective fever lasting at least 24 hours.

Reported Cases of Multisystem Inflammatory Syndrome in Children (MIS-C)
Data will be updated on the first and third Thursdays of the month.


Multisystem Inflammatory Syndrome in Children (MIS-C) Michigan Data Summary 1/7/2021
# Cases Confirmed and Reported to CDC* 58
MIS-C associated Deaths 5 or fewer
Cases admitted to ICU  42 (72.4%)
Onset Date Range 04/14/20 to 12/14/20
Age Range 0-20 years

*Meets CDC Case definition


Age Group Count % Race Count %
0-4 yrs 16 27.6% Black/African American 26 44.8%
5-10 yrs 24 41.4% Caucasian 26 44.8%
>10 yrs 18 31.0% All Others / Unknown 6 10.4%
Gender Counts % Ethnicity Count %
Male 28 48.3% Not Hispanic or Latino 33 56.9%
Female 30 51.7% Hispanic or Latino 6 10.3%
Unknown 0 0.0% Unknown 19 32.8%