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Environmental Mediators of Birth-defects and Relation to Contaminants (EMBARC)

Note: This website contains general information about the EMBARC study. If you received an invitation letter to join EMBARC, use the QR code or web address listed in your invitation letter to access your personal EMBARC study page.

The goal of the Environmental Mediators of Birth-defects and Relation to Contaminants (EMBARC) study is to learn if per- and polyfluoroalkyl substances (PFAS) might be linked to folate-sensitive birth defects.

Parents of young children are randomly selected to join EMBARC. Adults, over the age of 18, who are the parent or legal guardian of a child born recently in Michigan, are eligible. These parents receive invitation packets in the mail.

EMBARC is a case-control study. This means participants are selected in advance based on the outcome that researchers are studying. For EMBARC, the outcome being studied is folate-sensitive birth defects.

  • At this time, we are not accepting volunteers who have not been randomly selected during this process. If you are interested in learning more or speaking with study staff, call our hotline at 844-464-7327 and ask for EMBARC study staff.

You can learn more about folate, and folate-sensitive birth defects at the CDC's folic acid page.

Why is the EMBARC research study important?

Chemicals in the environment might be linked with certain birth outcomes, including folate-sensitive birth defects. EMBARC seeks to understand if newborn levels of one specific class of environmental chemicals, per- and polyfluoroalkyl substances (PFAS), are related to these birth defects.

Learn more about PFAS by visiting Michigan’s PFAS and Health page.

 

Contact EMBARC Study Staff by calling our hotline number 844-464-7327 or by emailing the study email address at MDHHS-EMBARC@michigan.gov.

Who can join EMBARC?

Randomly selected parents or legal guardians of children born in Michigan will be invited to join EMBARC. At this time, we are not accepting volunteers who were not randomly selected.

What will parents be asked to do?

Participation is completely online.

Parents will be asked to give permission for researchers to use their child’s unused newborn dried blood spot for PFAS testing. They are also asked to use information from birth records. Birth parents will also be asked to complete a short survey about their pregnancy.

Blood draws are not a part of this study. We will not ask for a new sample of blood as part of this research. Only historically collected and stored past samples of blood are tested for PFAS.

Learn more about newborn dried blood spots and BioTrust by visiting Michigan’s BioTrust for Health page.

You can learn more about Michigan’s newborn screening program by visiting Michigan's hereditary disorders page.

Why might parents want to join EMBARC?

  • Parents can learn the amount of PFAS that is in a past, stored sample of blood leftover from their child’s newborn screening.
  • Parents may contribute valuable information that may be used to better understand if a class of environmental chemicals, PFAS, is linked to some birth defects.
  • Participating parents may help other parents in the future by contributing to research that can impact policy decisions and public health practice.